Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey (tested or 100% immunogen sequence identity)
Bovine (at least 90% immunogen sequence identity)
IHC - Paraffin
Specificity and Use
ARHU / RHOU antibody was raised against synthetic peptide PPQQGDPAFPDRCEA from the N-terminus of human RHOU (NP_067028.1). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset (100%); Bovine (93%).
RHOU Antibody, ARHU Antibody, CDC42-like GTPase 1 Antibody, CDC42L1 Antibody, DJ646B12.2 Antibody, FJ646B12.2 Antibody, G28K Antibody, GTP-binding protein-like 1 Antibody, GTP-binding protein SB128 Antibody, HG28K Antibody, GTP-binding protein like 1 Antibody, Ras homolog family member U Antibody, Rho GTPase-like protein ARHU Antibody, Ryu GTPase Antibody, Ras-like gene family member U Antibody, Wnt-1 responsive Cdc42 homolog Antibody, WRCH-1 Antibody, WRCH1 Antibody
Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.