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Anti-ARHGEF4 Antibody (aa143-271, clone ARHGEF-08) LS-C204345


Wt. Vol. Conc. Price
100 µg - 1 mg/ml Unavailable

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Anti-ARHGEF4 Antibody (aa143-271, clone ARHGEF-08) LS-C204345
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Anti-ARHGEF4 Antibody (aa51-100, Biotin) LS-C466036
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Mouse Monoclonal [clone ARHGEF-08] (IgG1) to Human ARHGEF4
Western blot, Flow Cytometry


Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [ARHGEF-08]
Protein A purified


  • Western blot
  • Flow Cytometry

Specificity and Use

ARHGEF4 antibody was raised against recombinant fragment of human ARHGEF4 (amino acids 143-271).
Monoclonal antibody ARHGEF-08 recognizes human intracellular protein ARHGEF4 / ASEF1, approx. 80 kD guanine nucleotide exchange factor specific for Rac1 and Cdc42.
Flow Cytometry: Application note - intracellular staining.


PBS, pH 7.4, 15 mM sodium azide.
Store at 2-8°C. Do not freeze.
For research use only.


Q9NR80 NM_015320 NP_056135.2

ARHGEF4 Antibody, ASEF1 Antibody, ASEF Antibody, GEF4 Antibody, KIAA1112 Antibody, STM6 Antibody

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Requested From: 
Date Requested: 4/23/2017

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