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Anti-ARHGEF4 Antibody (aa143-271, clone ARHGEF-08) LS-C204345

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $265
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular ARHGEF4 Antibodies

Anti-ARHGEF4 Antibody (aa573-599, APC) LS-C232821
Rabbit Polyclonal (IgG) to Human ARHGEF4
Human
Western blot, ELISA
APC Conjugated
Anti-ARHGEF4 Antibody (aa573-599, Biotin) LS-C232822
Rabbit Polyclonal (IgG) to Human ARHGEF4
Human
Western blot, ELISA
Biotin Conjugated
Anti-ARHGEF4 Antibody (aa573-599, PE) LS-C232824
Rabbit Polyclonal (IgG) to Human ARHGEF4
Human
Western blot, ELISA
PE Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone ARHGEF-08] (IgG1) to Human ARHGEF4
Human
Western blot, Flow Cytometry
Unconjugated

Details

Human ARHGEF4
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [ARHGEF-08]
Unconjugated
Protein A purified
Unmodified

Applications

  • Western blot
  • Flow Cytometry

Specificity and Use

ARHGEF4 antibody was raised against recombinant fragment of human ARHGEF4 (amino acids 143-271).
aa143-271
Monoclonal antibody ARHGEF-08 recognizes human intracellular protein ARHGEF4 / ASEF1, approx. 80 kD guanine nucleotide exchange factor specific for Rac1 and Cdc42.
Flow Cytometry: Application note - intracellular staining.

Packaging

PBS, pH 7.4, 15 mM sodium azide.
Store at 2-8°C. Do not freeze.
For research use only.

About ARHGEF4

Q9NR80 NM_015320 NP_056135.2

ARHGEF4 Antibody, ASEF1 Antibody, ASEF Antibody, GEF4 Antibody, KIAA1112 Antibody, STM6 Antibody

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Requested From: United States
Date Requested: 12/10/2016

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