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Anti-APP / Beta Amyloid Precursor Antibody (aa360-409) LS-C109854

Ordering

Wt. Vol. Conc. Price
50 µg - - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular APP / Beta Amyloid Precursor Antibodies

Anti-APP / Beta Amyloid Precursor Antibody (Thr668) IHC-plus™ LS-B1462
Rabbit Polyclonal (IgG) to Human APP / Beta Amyloid Precursor
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-APP / Beta Amyloid Precursor Antibody (aa18-289, clone J4H9) IHC-plus™ LS-B2970
Mouse Monoclonal [clone J4H9] (IgG2b,k) to Human APP / Beta Amyloid Precursor
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-APP / Beta Amyloid Precursor Antibody (C-Terminus) LS-C193927
Rabbit Polyclonal (IgG) to Human APP / Beta Amyloid Precursor
Human, Mouse, Rat
Western blot, Immunoprecipitation
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human APP / Beta Amyloid Precursor
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human APP / Beta Amyloid Precursor
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Zebrafish (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

APP / Beta Amyloid Precursor antibody was raised against synthetic peptide located between aa360-409 of human APP (P05067, NP_000475). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus (100%); Lizard (92%); Zebrafish (91%).
LS-E12030 - Lyophilized - 100 µg - $145.00
aa360-409
human APP
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About APP / Beta Amyloid Precursor

P05067 NM_000484 NP_000475.1

APP Antibody, ABPP Antibody, A4 Antibody, ABETA Antibody, AD1 Antibody, Alzheimer disease Antibody, Amyloid beta Antibody, Beta-amyloid peptide Antibody, APPI Antibody, Beta amyloid Antibody, CVAP Antibody, AAA Antibody, PN2 Antibody, PreA4 Antibody, Amyloid beta A4 protein Antibody, Peptidase nexin-II Antibody, CTFgamma Antibody, PN-II Antibody, Protease nexin-II Antibody

Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP.

Western blot

Western blot
APP / Amyloid Precursor Protein antibody LS-C109854 Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/10/2016

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