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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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APLNR/ Apelin Receptor / APJ Antibody (Cytoplasmic Domain) IHC‑plus™ LS‑A64
APJ antibody LS-A64 is an unconjugated rabbit polyclonal antibody to APJ (APLNR / Apelin Receptor) from human and mouse. Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Catalog
Size
Price
LS-A64-50
50 µg (1 mg/ml)
Unavailable
In Stock for Immediate Shipment

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Product Description

APJ antibody LS-A64 is an unconjugated rabbit polyclonal antibody to APJ (APLNR / Apelin Receptor) from human and mouse. Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
About APLNR/ Apelin Receptor / APJ
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia. P35414 NM_005161 NP_005152.1

APLNR Antibody, AGTRL1 Antibody, Angiotensin receptor-like 1 Antibody, Angiotensin II receptor-like 1 Antibody, Apelin receptor Antibody, APJ Antibody, APJ (apelin) receptor Antibody, APJR Antibody, G protein-coupled receptor APJ Antibody, HG11 orphan receptor Antibody, HG11 Antibody, APJ receptor Antibody, G-protein coupled receptor APJ Antibody


Specifications

Target
Human APLNR/ Apelin Receptor / APJ
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (20 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human Apelin Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Bat, Horse, Rabbit (100%); Elephant (95%); Platypus (90%).
Epitope
Cytoplasmic Domain
Specificity
Human Apelin Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, less than 0.1% sodium azide.
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (1)

1
Apelin retards the progression of diabetic nephropathy. Day RT, Cavaglieri RC, Feliers D. American journal of physiology. Renal physiology. 2013 Mar;304:F788-800. [Full Text Article] [PubMed:23303408] [PMC:PMC3602700]

Customer Reviews (0)


Images


Immunohistochemistry

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry

Anti-APLNR/ Apelin Receptor / APJ antibody IHC of human brain vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-APLNR/ Apelin Receptor / APJ antibody IHC of human brain vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry

Anti-APLNR/ Apelin Receptor / APJ antibody IHC of human brain vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-APLNR/ Apelin Receptor / APJ antibody IHC of human brain vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry

Anti-APLNR/ Apelin Receptor / APJ antibody IHC of human brain vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-APLNR/ Apelin Receptor / APJ antibody IHC of human brain vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry

Anti-APLNR/ Apelin Receptor / APJ antibody IHC of human brain vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-APLNR/ Apelin Receptor / APJ antibody IHC of human brain vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.


Requested From: 
Date Requested: 6/18/2018

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