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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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AP‑1 / JUND Antibody (aa336‑347) LS‑C205030
Antibody
JUND antibody LS-C205030 is an unconjugated goat polyclonal antibody to JUND (AP-1) from human, mouse, rat and other species. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C205030-100
100 µg (0.5 mg/ml)
Unavailable

Popular AP-1 / JUND Products

Placenta Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Product Description

JUND antibody LS-C205030 is an unconjugated goat polyclonal antibody to JUND (AP-1) from human, mouse, rat and other species. Validated for Peptide-ELISA and WB.
About AP-1 / JUND
The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). P17535 NM_005354 NP_005345.3

JUND Antibody, Activator protein 1 Antibody, AP-1 Antibody, JunD-FL isoform Antibody, Jun D proto-oncogene Antibody, Transcription factor jun-D Antibody


Specifications

Target
Human AP-1 / JUND
Host
Goat
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Guinea pig, Pig, Chicken (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 3 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:64000)
Immunogen
AP-1 / JUND antibody was raised against synthetic peptide CQLLPQHQVPAY from the C-terminus of human AP-1 / JUND (NP_005345.3). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Mouse, Rat, Bovine, Pig, Guinea pig, Chicken, Platypus (100%); Ferret, Panda (92%); Xenopus (83%).
Epitope
aa336-347
Specificity
Human AP-1 / JUND. This antibody is expected NOT to cross-react with Jun oncogen (NP_002219.1, GeneID 3725)
Usage
Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 40kD band observed in nuclear lysates of cell line NIH3T3 (calculated MW of 35.2kD according to NP_005345.3). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Short and Pfarr, J Biol Chem. 2002 Sep 6.277(36):32697-705. PMID: 12105216). Recommended concentration: 1-3 ug/ml.
Presentation
Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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