Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle.
IHC of paraffin-embedded Cal27 xenograft using ANXA7 antibody at 1:100 dilution.
Annexin VII antibody detects ANXA7 protein at cytoplasm and nucleus by immunofluorescent analysis. HeLa cells were fixed in ice-cold MeOH for 5 min. ANXA7 protein stained by Annexin VII antibody diluted at 1:500.
Sample (30 ug of whole cell lysate). A:293T, B: A431. 7.5% SDS PAGE. Annexin VII / SNX antibody diluted at 1:2000