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Anti-AML1 / RUNX1 Antibody (clone 4E7) IHC-plus™ LS-B5383

Note: This antibody replaces LS-C133012

Catalog	Size	Price
LS-B5383-50	50 µg (0.3 mg/ml)	Unavailable

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103 AML1 / RUNX1 Antibodies

Most Popular AML1 / RUNX1 Antibodies

Anti-AML1 / RUNX1 Antibody (N-Terminus) IHC-plus™ LS-B998

Antibody:	Rabbit Polyclonal to Human AML1 / RUNX1
Reactivity:	Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Zebrafish
Application:	IHC - Paraffin, Western blot
Format:	Unconjugated

Anti-AML1 / RUNX1 Antibody (clone 3A1) IHC-plus™ LS-B5382

Antibody:	Mouse Monoclonal [clone 3A1] (IgG2b,k) to Human AML1 / RUNX1
Reactivity:	Human
Application:	IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Format:	Unconjugated

Anti-AML1 / RUNX1 Antibody (clone 4E7) IHC-plus™ LS-B5383

Antibody:	Mouse Monoclonal [clone 4E7] (IgG2b,k) to Human AML1 / RUNX1
Reactivity:	Human, Mouse
Application:	IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Format:	Unconjugated

Anti-AML1 / RUNX1 Antibody (Internal, clone 15B) LS-C191744

Antibody:	Rabbit Polyclonal [clone 15B] (IgG) to Human AML1 / RUNX1
Reactivity:	Human, Mouse
Application:	IHC - Paraffin, ICC, Western blot, ELISA
Format:	Unconjugated

Anti-AML1 / RUNX1 Antibody IHC-plus™ LS-B13948

Antibody:	Rabbit Polyclonal (IgG) to Human AML1 / RUNX1
Reactivity:	Human, Mouse, Rat
Application:	IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Format:	Unconjugated

Antibody:	Mouse Monoclonal [clone 4E7] (IgG2b,k) to Human AML1 / RUNX1
Reactivity:	Human, Mouse
Application:	IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Format:	Unconjugated

Details

Target:	Human AML1 / RUNX1
Host:	Mouse
Reactivity:	Human, Mouse (tested or 100% immunogen sequence identity)
Clonality:	IgG2b,k Monoclonal [4E7]
Conjugations:	Unconjugated
Purification:	Purified from ascites by Protein A
Modifications:	Unmodified

Applications

Approved:

IHC - Paraffin (5 µg/ml)
Immunofluorescence (10 µg/ml)
Western blot
ELISA

Specificity and Use

Immunogen:	AML1 / RUNX1 antibody was raised against rUNX1 (NP_001001890, 210 a.a. ~ 311 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity:	Human RUNX1
Usage:	Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot: Cell lysate, Cell lysate, Recombinant protein.

Packaging

Presentation:	PBS, pH 7.4.
Storage:	For long term, store at -20°C. Avoid repeat freeze-thaw cycles.
Restrictions:	For research use only.

About AML1 / RUNX1

Uniprot: Q01196 NCBI: NM_001754 NP_001745.2

Synonyms: RUNX1 Antibody, AMLCR1 Antibody, Aml1 oncogene Antibody, AML1 Antibody, AML1-EVI-1 Antibody, CBF-alpha-2 Antibody, CBFA2 Antibody, Acute myeloid leukemia 1 Antibody, EVI-1 Antibody, PEBP2A2 Antibody, PEA2-alpha B Antibody, AML1-EVI-1 fusion protein Antibody, Oncogene AML-1 Antibody, PEBP2-alpha B Antibody, PEBP2aB Antibody

Description: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter.

(More About AML1 / RUNX1)

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Technical Help Review

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Immunohistochemistry

Anti-RUNX1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5383 concentration 5 ug/ml.

Immunofluorescence

Immunofluorescence of monoclonal antibody to RUNX1 on HeLa cell. [antibody concentration 10 ug/ml]

Western blot

RUNX1 monoclonal antibody (M05), clone 4E7 Western blot of RUNX1 expression in HeLa NE.

Western blot

RUNX1 monoclonal antibody (M05), clone 4E7. Western blot of RUNX1 expression in NIH/3T3.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged RUNX1 is approximately 1 ng/ml as a capture antibody.

Requested From:
Date Requested: 6/25/2017

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