Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 5E1] (IgG2a) to Human Alpha-Fetoprotein Receptor
IHC - Paraffin, Western blot, ELISA
Human Alpha-Fetoprotein Receptor
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [5E1]
IHC - Paraffin
Specificity and Use
Purified human alpha fetoprotein receptor.
Recognizes alpha fetoprotein receptor (AFP receptor), a 62-67kD cell surface protein that mediates the uptake of AFP by proliferating or differentiating cells. AFP is expressed during gestation, but after birth levels in healthy adults drop to trace amounts. High expression of AFP and AFP receptor in adults can be indicative of certain cancers, especially hepatocellular carcinoma.
Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.