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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ADRA2C Antibody (aa309‑324) LS‑C49118
Note: This antibody replaces LS-C63764, LS-C63763
ADRA2C antibody LS-C49118 is an unconjugated rabbit polyclonal antibody to ADRA2C from human and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C49118-100
100 µg (1 mg/ml)
Unavailable

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Product Description

ADRA2C antibody LS-C49118 is an unconjugated rabbit polyclonal antibody to ADRA2C from human and rat. Validated for IHC and WB.
About ADRA2C
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. P18825 NM_000683 NP_000674.2

ADRA2C Antibody, ADRA2RL2 Antibody, ADRARL2 Antibody, Alpha-2C adrenergic receptor Antibody, Alpha-2c-2 adrenergic receptor Antibody, ADRA2L2 Antibody, Adrenoceptor alpha 2C Antibody, Alpha-2C-adrenergic receptor Antibody, Alpha-2C-AR Antibody, Alpha-2CAR Antibody, Alpha-2C adrenoceptor Antibody, Alpha-2C adrenoreceptor Antibody, Alpha2c Antibody, ALPHA2CAR Antibody, Alpha 2c Antibody, Alpha2-AR-C4 Antibody, Alpha2cii-adrenergic receptor Antibody


Specifications

Target
Human ADRA2C
Host
Rabbit
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC (1:100 - 1:300)
  • Western blot (1:500 - 1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ADRA2C antibody was raised against synthetic peptide comprising residues 309-324 [GAEGGAGGADGQGAGP] of the human Alpha 2c protein Percent identity by BLAST analysis: Human, Gibbon (100%); Monkey (88%).
Epitope
aa309-324
Specificity
Alpha-2C Adrenergic Receptor.
Presentation
PBS, 0.02% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Alpha 2C staining in rat ventral spinal cord. Detection was done using HRP-AEC staining reagents (red color), and tissues were counterstained with hematoxylin (blue color). Working dilution is 1:100-1:300
Alpha 2C staining in rat ventral spinal cord. Detection was done using HRP-AEC staining reagents (red color), and tissues were counterstained with hematoxylin (blue color). Working dilution is 1:100-1:300

Western blot

Western blot detection of Alpha 2c in 20 ug of human brain lysate (lane 2) with Alpha 2c polyclonal at 1:1000 dilution followed by AP-conjugated secondary at 1:5000 dilution. MW marker in Lane 1.
Western blot detection of Alpha 2c in 20 ug of human brain lysate (lane 2) with Alpha 2c polyclonal at 1:1000 dilution followed by AP-conjugated secondary at 1:5000 dilution. MW marker in Lane 1.

Immunohistochemistry

Alpha 2C staining in rat ventral spinal cord. Detection was done using HRP-AEC staining reagents (red color), and tissues were counterstained with hematoxylin (blue color). Working dilution is 1:100-1:300
Alpha 2C staining in rat ventral spinal cord. Detection was done using HRP-AEC staining reagents (red color), and tissues were counterstained with hematoxylin (blue color). Working dilution is 1:100-1:300

Western blot

Western blot detection of Alpha 2c in 20 ug of human brain lysate (lane 2) with Alpha 2c polyclonal at 1:1000 dilution followed by AP-conjugated secondary at 1:5000 dilution. MW marker in Lane 1.
Western blot detection of Alpha 2c in 20 ug of human brain lysate (lane 2) with Alpha 2c polyclonal at 1:1000 dilution followed by AP-conjugated secondary at 1:5000 dilution. MW marker in Lane 1.

Immunohistochemistry

Alpha 2C staining in rat ventral spinal cord. Detection was done using HRP-AEC staining reagents (red color), and tissues were counterstained with hematoxylin (blue color). Working dilution is 1:100-1:300
Alpha 2C staining in rat ventral spinal cord. Detection was done using HRP-AEC staining reagents (red color), and tissues were counterstained with hematoxylin (blue color). Working dilution is 1:100-1:300

Western blot

Western blot detection of Alpha 2c in 20 ug of human brain lysate (lane 2) with Alpha 2c polyclonal at 1:1000 dilution followed by AP-conjugated secondary at 1:5000 dilution. MW marker in Lane 1.
Western blot detection of Alpha 2c in 20 ug of human brain lysate (lane 2) with Alpha 2c polyclonal at 1:1000 dilution followed by AP-conjugated secondary at 1:5000 dilution. MW marker in Lane 1.

Immunohistochemistry

Alpha 2C staining in rat ventral spinal cord. Detection was done using HRP-AEC staining reagents (red color), and tissues were counterstained with hematoxylin (blue color). Working dilution is 1:100-1:300
Alpha 2C staining in rat ventral spinal cord. Detection was done using HRP-AEC staining reagents (red color), and tissues were counterstained with hematoxylin (blue color). Working dilution is 1:100-1:300

Western blot

Western blot detection of Alpha 2c in 20 ug of human brain lysate (lane 2) with Alpha 2c polyclonal at 1:1000 dilution followed by AP-conjugated secondary at 1:5000 dilution. MW marker in Lane 1.
Western blot detection of Alpha 2c in 20 ug of human brain lysate (lane 2) with Alpha 2c polyclonal at 1:1000 dilution followed by AP-conjugated secondary at 1:5000 dilution. MW marker in Lane 1.


Requested From: 
Date Requested: 6/21/2018

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