Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Monkey, Mouse, Rat, Bovine, Rabbit (tested or 100% immunogen sequence identity)
IHC - Paraffin (10 µg/ml)
Western blot (1:500 - 1:3000)
Specificity and Use
ADRA1A antibody was raised against synthetic peptide containing a sequence corresponding to a region within amino acids 206 and 270 of Human Alpha-1A adrenergic receptor.
Human Adrenergic receptor alpha 1a.
The antibody is predicted to cross-react with the following species based on their respective sequence homologies: mouse (100%), Rat (100%), Rabbit (100%), cow (100%), Monkey (100%. Cross-reactivity has not been experimentally confirmed at this time.
PBS, pH 7, 1% BSA, 20% Glycerol, 0.01% Thimerosal
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor.