Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human ACTC1 / Alpha Cardiac Actin
Human, Mouse, Rat
IHC - Paraffin, Western blot, ELISA
Rabbit Polyclonal to Human ACTC1 / Alpha Cardiac Actin
Human, Rat, Bovine, Pig, Chicken
IHC - Paraffin, Western blot
Human ACTC1 / Alpha Cardiac Actin
Human, Rat, Bovine, Pig, Chicken (tested or 100% immunogen sequence identity)
IHC - Paraffin (7.5 µg/ml)
Western blot (1:500 - 1:3000)
Specificity and Use
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 99 and 354 (P68032) of alpha Actin (cardiac muscle). Percent identity by BLAST analysis: Human, Chicken, Pig, Rat, Bovine (100%); Xenopus (99%).
Human ACTC1 / Alpha-Cardiac Actin
IHC-paraffin: Suggested antigen retrieval using heat mediated 10 mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0).
PBS, pH 7, 1% BSA, 20% Glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus.