Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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Mouse, Human (tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified
Applications
IHC - Paraffin (2.5 - 5 µg/ml)
Specificity and Use
ACCN1 / ASIC2 antibody was raised against synthetic peptide [CSGPGRFMAREQ] corresponding to aa15-26 of ASIC 2B. Percent identity by BLAST analysis: Mouse, Rat (92%).
aa15-26
Recognizes human ASIC 2B.
Suitable for use in Immunohistochemistry.
Packaging
PBS, 0.05% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
ACCN1 / ASIC2 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission.
Anti-ACCN1 antibody IHC of human cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4761 concentration 2.5 ug/ml.