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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ABCC3 / MRP3 Antibody (aa881‑894) LS‑C186434
Antibody
MRP3 antibody LS-C186434 is an unconjugated goat polyclonal antibody to human MRP3 (ABCC3). Validated for Peptide-ELISA.
Catalog
Size
Price
LS-C186434-100
100 µg (0.5 mg/ml)
Unavailable

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Product Description

MRP3 antibody LS-C186434 is an unconjugated goat polyclonal antibody to human MRP3 (ABCC3). Validated for Peptide-ELISA.
About ABCC3 / MRP3
ABCC3 / MRP3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. O15438 NM_003786 AAD02845.1

ABCC3 Antibody, ABC31 Antibody, EST90757 Antibody, MOAT-D Antibody, MLP2 Antibody, Multidrug resistance protein 3 Antibody, MRP3 Antibody, CMOAT2 Antibody


Specifications

Target
Human ABCC3 / MRP3
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine, Dog, Pig, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Peptide Enzyme-Linked Immunosorbent Assay (1:32000)
Immunogen
ABCC3 / MRP3 antibody was raised against synthetic peptide C-DTLSNHTDLTDNDP from an internal region of human ABCC3 / MRP3 (NP_003777.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan (100%); Monkey, Ferret, Rabbit, Pig, Bovine, Dog, Elephant (93%); Mouse, Panda (86%).
Blocking Peptide
LS-E27589 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C186434. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa881-894
Specificity
Human ABCC3 / MRP3. This antibody is expected to recognize reported isoform 1 (NP_003777.2;) only.
Usage
Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments in Human, Mouse and Rat Liver lysates gave no specific signal but low background (at antibody concentration up to 1 ug/ml).
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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