Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Primate (tested or 100% immunogen sequence identity)
Protein G purified
IHC - Paraffin
IHC - Frozen
Flow Cytometry (1:50 - 1:200)
Specificity and Use
ABCB1 / MDR1 / P Glycoprotein antibody was raised against mouse Balb/c 3T3 fibroblasts transfected with human CD243 cDNA.
Recognizes human CD243. Species cross-reactivity: primate. Does not react with: mouse, rat.
Suitable for use in Flow Cytometry, Functional Assays, Immunofluorescence, Immunohistochemistry (frozen and paraffin), and Immunoprecipitation. Flow Cytometry: 1:50-1:200; 10 ul labels 10^6 cells in 100ul.
PBS, pH 7.4. No preservative added
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance.