Human ANPEP / CD13
ANPEP | Alanyl aminopeptidase | Aminopeptidase M | APN | Aminopeptidase N | AP-N | AP-M | CD13 | CD13 antigen | HAPN | gp150 | p150 | PEPN | Microsomal aminopeptidase | LAP1
(tested or 100% immunogen sequence identity)
Also available conjugated with RPE
Ion exchange chromatography
Also available Low Endotoxin
Recognizes human CD13 also known as aminopeptidase N. CD13 is a single pass type II glycosylated integral membrane protein with a predicted molecular mass of ~110 kD and an apparent molecular mass of ~150 kD expressed by granulocytes, monocytes, fibroblasts, endothelial cells and by myeloid leukaemia cells. CD13 acts as a major cell surface receptor for group 1 coronoviruses which bind to a critical sequence encompassing amino acid residues 288-295. CD13 functions as an enzyme, a metalloprotease present as both a membrane bound form and also a soluble aminopeptidase N. Inhibits infection of cells by human coronavirus but not hepatitis C virus and inhibits aminopeptidase N activity of the CD13 molecule.