Human ALOX12 / 12 Lipoxygenase

Rabbit

Human (tested or 100% immunogen sequence identity)

Horse (at least 90% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

Synthetic peptide from the C-Terminus of human ALOX12 (HHKEKYFSGPKPKAVLNQFR, aa609-628 of UniProt P18054). Percent identity by BLAST analysis: Human (100%); Horse (90%); Ferret, Dog (85%); Sheep, Cat, Bovine, Bat, Elephant, Pig (80%); Rat (75%); Mouse (70%).

aa609-628

Human ALOX12 / 12 Lipoxygenase

• Western blot (0.5 - 1 µg/ml)

Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of DNAArachidonate 12-lipoxygenase introduces a molecular oxygen into the C-12 position of arachidonic acid to produce 12 (S)-hydroperoxy-5,8,10,14-eicosatetraenoic acid. The major pathway of arachidonic acid metabolism in human platelets proceeds via a 12-lipoxygenase enzyme. Expression of the LOG12 gene was detected in human erythroleukemia cells, platelets, and human umbilical vein endothelial cells by reverse transcription-PCR analysis.

Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.

Reconstitute in sterile distilled water.

Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P18054 NCBI: NM_000697 NP_000688.2