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Catalog Number Size Price
LS-C388039-100 100 µg $506 
AHR Antibody - Western blot testing of Aryl hydrocarbon Receptor antibody and human samples 1: PANC; 2: HeLa; 3: MCF-7; 4: HT1080 cell lysate. Predicted molecular weight ~ 95kDa.

Polyclonal Rabbit anti‑Human AHR Antibody (aa832‑848, WB) LS‑C388039

Polyclonal Rabbit anti‑Human AHR Antibody (aa832‑848, WB) LS‑C388039

Antibody:
AHR Rabbit anti-Human Polyclonal (aa832-848) Antibody
Application:
WB
Reactivity:
Human, Pig
Format:
Unconjugated, Unmodified
Price
Catalog Number
$506
LS-C388039-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
AHR Rabbit anti-Human Polyclonal (aa832-848) Antibody
Application:
WB
Reactivity:
Human, Pig
Format:
Unconjugated, Unmodified

Specifications

Description
AHR antibody LS-C388039 is an unconjugated rabbit polyclonal antibody to AHR (aa832-848) from human. It is reactive with human and pig. Validated for WB.
Target
Human AHR
Synonyms
AHR | Ah receptor | AH-receptor | Aryl hydrocarbon receptor | BHLHe76 | Aromatic hydrocarbon receptor
Host
Rabbit
Reactivity
Human, Pig (tested or 100% immunogen sequence identity)
Predicted
Bovine, Dog (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Amino acids 832-848 (HPSEARPFPDLTSSGFL-human) were used as the immunogen for this Aryl hydrocarbon Receptor antibody. Percent identity by BLAST analysis: Human, Pig (100%); Ferret, Bovine, Dog (94%); Cat, Horse (88%); Sheep, Bat, Elephant, Guinea pig (82%); Mouse (65%).
Epitope
aa832-848
Specificity
Human AHR
Applications
  • Western blot (0.5 - 1 µg/ml)
Usage
Aryl hydrocarbon receptor, also called AHR and bHLHe76, is a member of the family of basic helix-loop-helix transcription factors. It is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones. The gene is mapped on 7p21.1. Estrogenic actions of AHR agonists were detected in wildtype ovariectomized mouse uteri, but were absent in Ahr-/- or Er-alpha -/- ovariectomized mice. CD4-positive cells from mice lacking the recepter developed Th17 responses but failed to produce IL-22 and did not show enhanced Th17 development. Activation of Aryl hydrocarbon receptor during induction of EAE accelerated disease onset and increased pathology in wildtype mice, but not in -/- mice. The TDO-AHR pathway is active in human brain tumors and is associated with malignant progression and poor survival. Activity within ROR-gamma-t-positive ILC could be induced by dietary ligands such as those contained in vegetables of the family Brassicaceae.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About AHR
P35869 NM_001621 NP_001612.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 12/1/2021