Products
Services
Research Areas
COVID-19
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-C134868-1 1 ml $455 
Antibody

Monoclonal Rat anti‑Human ABCC6 / MRP6 Antibody (clone M6II‑31, Concentrated, IHC, WB) LS‑C134868

Monoclonal Rat anti‑Human ABCC6 / MRP6 Antibody (clone M6II‑31, Concentrated, IHC, WB) LS‑C134868

Antibody:
Rat Monoclonal to Human ABCC6 / MRP6
Application:
IHC, IHC-P, IHC-Fr, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Concentrated
Price
Catalog Number
$455 
LS-C134868-1
1 ml
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rat Monoclonal to Human ABCC6 / MRP6
Application:
IHC, IHC-P, IHC-Fr, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Concentrated

Specifications

Description
MRP6 antibody LS-C134868 is an unconjugated rat monoclonal antibody to human MRP6 (ABCC6). Validated for Flow, IHC and WB.
Target
Human ABCC6 / MRP6
Synonyms
ABCC6 | ABC34 | EST349056 | MLP1 | MOAT-E | MRP6 | MOATE | URG7 | PXE1 | ARA | GACI2 | Pseudoxanthoma elasticum | PXE
Host
Rat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Clone
M6II-31
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Concentrated
Applications
  • IHC
  • IHC - Paraffin
  • IHC - Frozen
  • Western blot
  • Flow Cytometry
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Specificity
M6II-31 reacts with MRP6, a 190-200 kD transmembrane protein that is related to the multidrug resistance related protein MRP. Mutations in the MRP6 gene are responsible for the connective tissue disorder Pseudoxanthoma elasticum (PXE). M6II-31 was raised against a bacterial fusion protein of human MRP6, containing amino acids 764-964, spanning the putative 12th transmembrane region as well as predicted internal and external regions of the protein. M6II-7 did not cross-react with the human MDR1, MRP1, MRP2, MRP3, MRP4, MRP5 gene products.
Usage
M6II-31 can be used to detect human MRP6 in cells and tissues. Immunocytochemistry: use 1:20-50 dilution on acetone fixed cytospin preparations. For immunohistochemistry: M6II-31 (use 1:20-50) on acetone fixed frozen sections can be followed by incubation with rabbit anti-rat IgG (1:25, Dako) and an APAAP complex (1:50, Dako). M6II-31 can be used on formaldehyde-fixed paraffin-embedded human tissues, after pretreatment with 0.01 M citric acid (pH 6.0) in distilled water at 100 C for 10 minutes. After incubation of M6II-31 (use 1:20) and washing, slides can be incubated with biotinylated rabbit anti-rat IgG (1:100, Jackson, West Grove) and streptavidin conjugated to horseradish peroxidase (1:500, Zymed, San Francisco, CA). Flow cytometry: optimal conditions still to be defined. Western blotting: use 1:20-50 dilution and anti-rat-HRP.
Presentation
Tissue Culture Supernatant, 0.1% Sodium Azide, 0.7% BSA, Serum-free
Storage
Store at 2-8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ABCC6 / MRP6
O95255 NM_001171 NP_001162.4

Publications (0)

Customer Reviews (0)


Requested From: United States
Date Requested: 6/5/2020