ITGAM / CD11b Antibody (clone ITGAM/271)
Catalog Number: LS-C761431
2 sizes / from $379.00
Antibody: Mouse Monoclonal
Applications: Flow Cytometry, Immunofluorescence
Reactivity: Human
Format: Liquid
Anti-CD11b antibody IHC of mouse spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
PathPlus™ ITGAM / CD11b Antibody (clone M1/70.15)
Primary AntibodyLSBio Guarantee
| Antibody: | Rat Monoclonal |
| Applications: | Flow Cytometry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Immunoprecipitation |
| Reactivity: | Human, Mouse, Rabbit |
| Format: | Liquid |
$470.00each
Catalog Number: LS-B3760-0.05
Catalog Number: LS-B3760
For bulk orders or custom formulations:
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- Description
- CD11b antibody LS-B3760 is an unconjugated rat monoclonal antibody to CD11b (ITGAM) from mouse. It is reactive with human, mouse and rabbit. Validated for Flow, IF, IHC and IP.
- Application
- FC, IF, IHC, IHC-F, IHC-P, IP
- Reactivity
- Hu, Ms, Rb
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain | ITGAM
- UniProt Number
- P11215
- NCBI GenBank
- NM_000632 | NP_000623.2
- SwissProt
- P11215
Recommended Dilution
| Application | Dilution |
|---|---|
| FC | 1:50 |
| IHC-P | 10 µg/ml |
Target
- Target
- ITGAM / CD11b
- Antigen Species
- Mouse
- Specificity
- Mouse, human, rabbit ITGAM
- Epitope
- Recognizes the murine CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone M1/70.15 has been reported to block iC3b binding to its receptor. This product is routinely tested in flow cytometry on mouse peritoneal macrophages.
- Gene Name
- ITGAM
Antibody
- Host Species
- Rat
- Clonality
- Monoclonal
- Clone
- M1/70.15
- Origin Species
- Human
Immunogen
- Immunogen
- T cell enriched splenocytes from B10 mice
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Ion Exchange Chromatography
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS
