ITGAM / CD11b Antibody (clone 5C6, Low Endotoxin)
Primary AntibodyLSBio Guarantee
| Antibody: | Rat Monoclonal |
| Applications: | Flow Cytometry, Immunofluorescence, Immunohistochemistry, Frozen, Immunoprecipitation |
| Reactivity: | Mouse |
| Format: | Liquid |
$654.00each
Catalog Number: LS-C188734-0.5
Catalog Number: LS-C188734
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- Description
- CD11b antibody LS-C188734 is an unconjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow, IF, IHC and IP.
- Application
- FC, IF, IHC-F, IP
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain | ITGAM
- Recommended Dilution: FC
- 1:50 - 1:100
- UniProt Number
- P11215
- NCBI GenBank
- NM_000632 | NP_000623.2
- SwissProt
- P11215
Target
- Target
- Mouse ITGAM / CD11b
- Antigen Species
- Mouse
- Epitope
- Recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. The antibody immunoprecipitates a heterodimer of 165 and 95kD. Clone 5C6 exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.
- Gene Name
- ITGAM
Antibody
- Host Species
- Rat
- Clonality
- Monoclonal
- Clone
- 5C6
- Isotype
- IgG2b
Immunogen
- Immunogen
- Thioglycollate-elicited Peritoneal Macrophages (TPM).
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS