ITGAM / CD11b Antibody (clone 5C6)

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Antibody:	Rat Monoclonal
Applications:	Flow Cytometry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunoprecipitation
Reactivity:	Mouse
Format:	Liquid

$444.00each

Catalog Number: LS-C188733-0.25

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Description: CD11b antibody LS-C188733 is an unconjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow, IF, IHC and IP.
Application: FC, IF, IHC, IHC-F, IP
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain | ITGAM
Recommended Dilution: FC: 1:100
UniProt Number: P11215
NCBI GenBank: NM_000632 | NP_000623.2
SwissProt: P11215

Target: Mouse ITGAM / CD11b
Antigen Species: Mouse
Epitope: Recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. The antibody immunoprecipitates a heterodimer of 165 and 95kD. Clone 5C6 exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.
Gene Name: ITGAM

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS

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