ITGAM / CD11b Antibody (clone 5C6, RPE)
Primary AntibodyLSBio Guarantee
| Antibody: | Rat Monoclonal |
| Applications: | Flow Cytometry |
| Reactivity: | Mouse |
| Format: | Lyophilized |
$474.00each
Catalog Number: LS-C188736-100
Catalog Number: LS-C188736
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- Description
- CD11b antibody LS-C188736 is an RPE-conjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow.
- Application
- FC
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain | ITGAM
- Recommended Dilution: FC
- 1:10
- UniProt Number
- P11215
- NCBI GenBank
- NM_000632 | NP_000623.2
- SwissProt
- P11215
Target
- Target
- Mouse ITGAM / CD11b
- Antigen Species
- Mouse
- Epitope
- Recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Clone 5C6 immunoprecipitates a heterodimer of 165 and 95kD. Clone 5C6 also exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. This clone also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.
- Gene Name
- ITGAM
Antibody
- Host Species
- Rat
- Clonality
- Monoclonal
- Clone
- 5C6
- Isotype
- IgG2b
Immunogen
- Immunogen
- Thioglycollate-elicited Peritoneal Macrophages (TPM).
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Phycoerythrin
- Format
- Lyophilized
- Formulation
- PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
- Preservative
- Yes
- Purification Method
- Ion Exchange Chromatography
Storage & Handling
- Storage Conditions
- Store at 4°C. Do not freeze. Store untiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS