HeLa lysate probed with Rabbit anti-Human MAP1LC3A/B (N-terminal) followed by Sheep anti-Rabbit IgG:HRP

MAP1LC3A / LC3A Antibody (aa2-15)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Immunofluorescence, Western Blot
Reactivity:	Human
Format:	Liquid

$519.00each

Catalog Number: LS-C188005-0.1

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Description: LC3A antibody LS-C188005 is an unconjugated rabbit polyclonal antibody to human LC3A (MAP1LC3A) (aa2-15). Validated for IF and WB.
Application: IF, WB
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: ATG8E | LC3 | LC3A | MAP1BLC3 | MAP1LC3A | MAP1A/1B light chain 3 A | MAP1A/MAP1B LC3 A | MAP1A/MAP1B light chain 3 A | MAP1ALC3
Recommended Dilution: WB: 1:100 - 1:250
UniProt Number: Q9H492
NCBI GenBank: NM_032514 | NP_115903.1
SwissProt: Q9H492

Target: Human MAP1LC3A / LC3A
Antigen Species: Human
Epitope: Recognizes an epitope within the N-Terminal (NT) region of both MAP1LC3A (Microtubule-associated proteins 1A/1B light chain 3A/LC3A) and MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B/LC3B), ubiquitin-like proteins and members of the MAP1LC3 family, which are widely used as reliable markers for the monitoring of autophagy. LC3-I is the cytosolic form of LC3, which is converted into the active, membrane-bound form LC3-II, during the autophagy process. Tracking the level of conversion of LC3-I to LC3-II provides an indicator of autophagic activity, and levels of LC3-II in particular, correlate with the extent of autophagosome formation, due to its association with the autophagosome membrane. Recognizes both the LC3-I and LC3-II forms of MAP1LC3A and MAP1LC3B.
Gene Name: MAP1LC3A

Immunogen: Synthetic peptide sequence PSDRPFKQRRSFADC from the N-Terminus of LC3A (NP_115903.1; NP_852610.1). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Bovine, Pig, Opossum, Guinea pig, Salmon, Zebrafish (100%); Ferret, Dog, Cat, Lizard, Catfish, Stickleback, Medaka, Pufferfish (93%); Chicken, Pike (86%).
Immunogen Type: Synthetic Peptide (Linear)

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS

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