ITGAM / CD11b Antibody (clone CA16.3E10, Supernatant)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunohistochemistry, Frozen, Immunoprecipitation |
| Reactivity: | Dog |
| Format: | Liquid |
$505.00each
Catalog Number: LS-C188175-2
Catalog Number: LS-C188175
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- Description
- CD11b antibody LS-C188175 is an unconjugated mouse monoclonal antibody to dog CD11b (ITGAM). Validated for Flow, IHC and IP.
- Application
- FC, IHC-F, IP
- Reactivity
- Can
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain | ITGAM
- Recommended Dilution: FC
- 0.0423611111111111
- UniProt Number
- P11215
- NCBI GenBank
- NM_000632 | NP_000623.2
- SwissProt
- P11215
Target
- Target
- Dog ITGAM / CD11b
- Antigen Species
- Dog
- Epitope
- Is a monoclonal antibody recognizing the canine CD11b cell surface antigen, a member of the alpha integrin family. CD11b forms one of the possible alpha chains of the canine leukocyte adhesion complexes (LeuCAMs), these contain a common 95 kD beta chain non-covalently bound to either a 150 kD, 165 kD (CD11b) or 180 kD (CD11a) alpha chain. The CD11/CD18 complex is also known as the CR3 receptor. Canine CD11b is expressed by granulocytes, monocytes, NK cells and some macrophages. Has been used to evaluate the effect of anesthetic administration of CD11b expression on canine neutrophils demonstrating attenuation of CD11b expression at high concentrations administered lidocaine hydrochloride and reduced adhesion of neutrophils to endothelium.
- Gene Name
- ITGAM
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- CA16.3E10
- Isotype
- IgG1
Immunogen
- Immunogen
- Affinity purified beta-2 integrins from splenic lysate.
- Immunogen Type
- Tissue Extract
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.1% Sodium Azide
- Volume
- 2 Milliliter
- Preservative
- Yes
- Purification Method
- Unpurified (Serum / Ascites / Supernatant)
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS