ITGAM / CD11b Antibody (clone ED8)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Immunohistochemistry, Frozen |
| Reactivity: | Rat |
| Format: | Liquid |
$415.00each
Catalog Number: LS-C188728-0.25
Catalog Number: LS-C188728
For bulk orders or custom formulations:
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- Description
- CD11b antibody LS-C188728 is an unconjugated mouse monoclonal antibody to rat CD11b (ITGAM). Validated for IHC.
- Application
- IHC-F
- Reactivity
- Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain | ITGAM
- UniProt Number
- P11215
- NCBI GenBank
- NM_000632 | NP_000623.2
- SwissProt
- P11215
Target
- Target
- Rat ITGAM / CD11b
- Antigen Species
- Rat
- Epitope
- Recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. It also recognizes small ramified microglia in the central nervous system. No other cell types are positive for ED8. The recognized antigen is a heterodimer (160 and 95kD) belonging to the family of adhesion molecules CD11b/CD18, also designated as Mac-1 antigen or CR3. ED7 and ED8 may recognize closely related epitopes on the same molecule. ED7 and ED8 have been shown to induce homotypic aggregation of granulocytes.
- Gene Name
- ITGAM
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- ED8
- Isotype
- IgG1
Immunogen
- Immunogen
- Rat spleen cell homogenate with FCA.
- Immunogen Type
- Tissue Extract
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS