LSBio
Polyclonal Rabbit anti-Mouse ACCN1 / ASIC2 Antibody (aa350-400, IHC, WB)

Polyclonal Rabbit anti-Mouse ACCN1 / ASIC2 Antibody (aa350-400, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Western Blot
Reactivity:Human, Mouse, Rat
Format:Lyophilized
See all Mouse ACCN1 / ASIC2 antibodies →
$401.00each
Catalog Number: LS-C93915-100

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Overview

Description
ASIC2 antibody LS-C93915 is an unconjugated rabbit polyclonal antibody to ASIC2 (ACCN1) (aa350-400) from mouse. It is reactive with human, mouse and rat. Validated for IHC and WB. Cited in 6 publications.
Application
IHC, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
ACCN1 | ASIC2a | ASIC2 | Brain sodium channel 1 | Degenerin | ACCN | Acid-sensing ion channel 2 | Mammalian degenerin homolog | MDEG | MDEG1 | MDEG2 | HBNaC1 | BNaC1 | MAMMALIAN DEGENERIN | ASIC2b
UniProt Number
Q16515
SwissProt
Q16515

Target

Target
Mouse ACCN1 / ASIC2
Antigen Species
Mouse
Epitope
Specific for ACCN1.
Gene Name
ASIC2

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide from the extracellular domain of mouse amiloride sensitive cation channel 1, neuronal (ACCN1, ASIC2) conjugated to an immunogenic carrier protein. The antigen is homologous in human and rat.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized
Volume
100 Microliter
Preservative
No
Purification Method
Unpurified (Serum / Ascites / Supernatant)

Storage & Handling

Storage Conditions
Maintain lyophilized and reconstituted antibodies at -20°C for long term storage and at 2°C to 8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze/thaw cycles.

Regulation of acid-sensing ion channel 1a function by tissue kallikrein may be through channel cleavage. Jingjing Su, Yuping Tang, Ling Liu, Houguang Zhou, Qiang Dong. Neuroscience letters. 2011;490:46-51.

PubMed: 21167908


Immunohistochemical Detection of the Putative Mechanoproteins ASIC2 and TRPV4 in Avian Herbst Sensory Corpuscles. Cabo R, Gálvez A, Laurà R, San José I, Pastor JF, López-Muñiz A, García-Suárez O, Vega JA. Anatomical record (Hoboken, N.J. : 2007). 2013;296:117-22.

PubMed: 23152301


The sensory innervation of the human pharynx: searching for mechanoreceptors. de Carlos F, Cobo J, Mac[Character ed]as E, Feito J, Cobo T, Calavia MG, Garc[Character ed]a-Su[Character e1]rez O, Vega JA. Anatomical record (Hoboken, N.J. : 2007). 2013 Nov;296:1735-46.

PubMed: 24123994


Acid-sensing ion channel 2 (ASIC2) in the intestine of adult zebrafish. Levanti MB, Guerrera MC, Calavia MG, Ciriaco E, Montalbano G, Cobo J, German[Character e0] A, Vega JA. Neuroscience letters. 2011 Apr;494:24-8.

PubMed: 21356277


Immunohistochemical localization of acid-sensing ion channel 2 (ASIC2) in cutaneous Meissner and Pacinian corpuscles of Macaca fascicularis. Cabo R, G[Character e1]lvez MA, San Jos[Character e9] I, Laur[Character e0] R, L[Character f3]pez-Mu[Character f1]iz A, Garc[Character ed]a-Su[Character e1]rez O, Cobo T, Insausti R, Vega JA. Neuroscience letters. 2012 May;516:197-201.

PubMed: 22708125


ASIC2 is present in human mechanosensory neurons of the dorsal root ganglia and in mechanoreceptors of the glabrous skin. Cabo R, Alonso P, Vi[Character f1]a E, V[Character e1]zquez G, Gago A, Feito J, P[Character e9]rez-Molt[Character f3] FJ, Garc[Character ed]a-Su[Character e1]rez O, Vega JA. Histochemistry and cell biology. Mar;143:267-76.

PubMed: 25224144

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