LSBio
Polyclonal Rabbit anti-Human ACCN1 / ASIC2 Antibody (aa481-530, IHC, WB)

Anti-ACCN1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Polyclonal Rabbit anti-Human ACCN1 / ASIC2 Antibody (aa481-530, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
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$383.00each
Catalog Number: LS-B156-100

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Overview

Description
ASIC2 antibody LS-B156 is an unconjugated rabbit polyclonal antibody to human ASIC2 (ACCN1) (aa481-530). Validated for IHC and WB. Cited in 5 publications.
Application
IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
ACCN1 | ASIC2a | ASIC2 | Brain sodium channel 1 | Degenerin | ACCN | Acid-sensing ion channel 2 | Mammalian degenerin homolog | MDEG | MDEG1 | MDEG2 | HBNaC1 | BNaC1 | MAMMALIAN DEGENERIN | ASIC2b
Recommended Dilution: IHC-P
5 µg/ml
UniProt Number
Q16515
SwissProt
Q16515

Target

Target
ACCN1 / ASIC2
Antigen Species
Human
Specificity
Human ACCN1
Epitope
Human ACCN1
Gene Name
ASIC2

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide located between aa481-530 of human ASIC2 (Q16515-2, NP_899233). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Marmoset, Elephant, Bat, Rabbit, Horse (100%); Galago, Mouse, Rat, Bovine, Opossum, Turkey, Chicken (92%); Zebra finch (85%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% sodium azide, 2% sucrose
Concentration
0.5 mg/mL
Volume
100 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS

Acid-sensing ion channels in healthy and degenerated human intervertebral disc. Cuesta A, Del Valle ME, Garc[Character ed]a-Su[Character e1]rez O, Vi[Character f1]a E, Cabo R, V[Character e1]zquez G, Cobo JL, Murcia A, Alvarez-Vega M, Garc[Character ed]a-Cosamal[Character f3]n J, Vega JA. Connective tissue research. 2014 Jun;55:197-204.

PubMed: 24432912


Acid-sensing ion channels (ASICs) in the taste buds of adult zebrafish. Vi[Character f1]a E, Parisi V, Cabo R, Laur[Character e0] R, L[Character f3]pez-Velasco S, L[Character f3]pez-Mu[Character f1]iz A, Garc[Character ed]a-Su[Character e1]rez O, German[Character e0] A, Vega JA. Neuroscience letters. 2013 Mar;536:35-40.

PubMed: 23328442


Acid-sensing ion channels (ASICs) 2 and 4.2 are expressed in the retina of the adult zebrafish. Parisi V, S[Character e1]nchez-Ramos C, Cabo R, Guerrera MC, Quir[Character f3]s LM, German[Character e0] A, Vega JA, Garc[Character ed]a-Su[Character e1]rez O. Cell and tissue research. Jan.

PubMed: 25585988


Acid-sensing ion channel 2 (ASIC2) is selectively localized in the cilia of the non-sensory olfactory epithelium of adult zebrafish. Vi[Character f1]a E, Parisi V, Abbate F, Cabo R, Guerrera MC, Laur[Character e0] R, Quir[Character f3]s LM, P[Character e9]rez-Varela JC, Cobo T, German[Character e0] A, Vega JA, Garc[Character ed]a-Su[Character e1]rez O. Histochemistry and cell biology. 2015 Jan;143:59-68.

PubMed: 25161120


Acid-sensing ion channel 2 (asic 2) and trkb interrelationships within the intervertebral disc. Cuesta A, Viña E, Cabo R, Vázquez G, Cobo R, García-Suárez O, García-Cosamalón J, Vega JA. International journal of clinical and experimental pathology. 2015;8:10305-14.

PubMed: 26617738 · PMC: PMC4637553

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