LSBio
Monoclonal Mouse anti-Human CD209 / DC-SIGN Antibody (clone MR-1, Low Endotoxin, IF)

Flow cytometry of CD209 transfected K562 cells with Mouse anti-Human CD209. This image was taken for the unmodified form of this product. Other forms have not been tested.

Monoclonal Mouse anti-Human CD209 / DC-SIGN Antibody (clone MR-1, Low Endotoxin, IF)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunofluorescence
Reactivity:Human
Format:Liquid
See all Human CD209 / DC-SIGN antibodies →
$654.00each
Catalog Number: LS-C44680-0.5

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Overview

Description
DC-SIGN antibody LS-C44680 is an unconjugated mouse monoclonal antibody to human DC-SIGN (CD209). Validated for Flow and IF.
Application
FC, IF
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD209 antigen | CD209 molecule | CDSIGN | CLEC4L | CD209 | DC-SIGN | HIV gpl20-binding protein | DC-SIGN1
UniProt Number
Q9NNX6
NCBI GenBank
NM_021155 | NP_066978.1
SwissProt
Q9NNX6

Target

Target
Human CD209 / DC-SIGN
Antigen Species
Human
Epitope
Recognizes human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45kD C-type lectin that binds ICAM-3 that is also known as CD209. CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DCs in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DCs and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DCs. Clone MR-1 is reported to partially block the functional activity of DC-SIGN(2).
Gene Name
CD209

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
MR-1
Isotype
IgG1

Immunogen

Immunogen
Immature myeloid monocyte-derived dendritic cells (MDDCs)
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS
Concentration
1 mg/mL
Preservative
No
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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