Flow cytometry of CD209 transfected K562 cells with Mouse anti-Human CD209. This image was taken for the unmodified form of this product. Other forms have not been tested.
CD209 / DC-SIGN Antibody (clone MR-1, RPE)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry |
| Reactivity: | Human |
| Format: | Lyophilized |
$413.00each
Catalog Number: LS-C44681-100
Catalog Number: LS-C44681
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- Description
- DC-SIGN antibody LS-C44681 is an RPE-conjugated mouse monoclonal antibody to human DC-SIGN (CD209). Validated for Flow.
- Application
- FC
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD209 antigen | CD209 molecule | CDSIGN | CLEC4L | CD209 | DC-SIGN | HIV gpl20-binding protein | DC-SIGN1
- Recommended Dilution: FC
- 1:1 - 1:10
- UniProt Number
- Q9NNX6
- NCBI GenBank
- NM_021155 | NP_066978.1
- SwissProt
- Q9NNX6
Target
- Target
- Human CD209 / DC-SIGN
- Antigen Species
- Human
- Epitope
- Recognizes human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45kD C-type lectin that binds ICAM-3 which is also known as CD209. CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DCs in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DCs and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DCs. Clone MR-1 is reported to partially block the functional activity of DC-SIGN(2). XXX recommend the use of MCA2318EL for this purpose.
- Gene Name
- CD209
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- MR-1
- Isotype
- IgG1
Immunogen
- Immunogen
- Immature myeloid monocyte-derived dendritic cells (MDDCs)
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Phycoerythrin
- Format
- Lyophilized
- Formulation
- PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C. Do not freeze. Store untiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS