LSBio
IHC-plus™ Monoclonal Mouse anti-Human ITGB2 / CD18 Antibody (clone MEM-48, IHC, WB)

Anti-ITGB2 / CD18 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ Monoclonal Mouse anti-Human ITGB2 / CD18 Antibody (clone MEM-48, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all ITGB2 / CD18 antibodies →
$470.00each
Catalog Number: LS-B1849-0.05

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Overview

Description
CD18 antibody LS-B1849 is an unconjugated mouse monoclonal antibody to human CD18 (ITGB2). Validated for Flow, Func, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
IHC
Reactivity
Hu
Nonreactive Species
Dog
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD18 antigen | CD18 | Integrin beta chain, beta 2 | ITGB2 | LCAMB | MAC-1 | MFI7 | MF17 | Integrin beta-2 | LAD | LFA-1
Recommended Dilution: FC
2 µg/ml
Recommended Dilution: IHC-P
10 µg/ml
Recommended Dilution: IP
2 µg/ml
Recommended Dilution: WB
2 µg/ml
UniProt Number
P05107
SwissProt
P05107

Target

Target
ITGB2 / CD18
Antigen Species
Human
Specificity
The antibody MEM-48 recognizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit; beta2 integrin). CD18 is a 90-95 kDa type I transmembrane protein expressed on all leukocytes.
Epitope
The antibody MEM-48 recognizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit; beta2 integrin). CD18 is a 90-95 kDa type I transmembrane protein expressed on all leukocytes.
Gene Name
ITGB2

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
MEM-48
Origin Species
Human

Immunogen

Immunogen
Leukocytes of a patient suffering from a LGL-type leukemia

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 15 mM Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C. Do not freeze.
Recommended Storage Buffer
PBS
Expression of adhesion, attachment and invasion markers in eutopic and ectopic endometrium: a link to the aetiology of endometriosis. Sundqvist J, Andersson KL, Scarselli G, Gemzell-Danielsson K, Lalitkumar PG. Human reproduction (Oxford, England). 2012 Sep;27:2737-46. PubMed: 22767451

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