Western Blotting analysis of PMA-activated neutrophils (A) and monocytes (B), using anti-human CD18 (MEM-148). The antibody MEM-148 recognizes the lower 65 to 70 kDa zone (activation marker) as well as the upper 78 to 96 kDa zone (CD18).
ITGB2 / CD18 Antibody (clone MEM-148)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Functional Assay, Immunohistochemistry (general), Immunoprecipitation, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$323.00each
Catalog Number: LS-C45978-0.1
Catalog Number: LS-C45978
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- Description
- CD18 antibody LS-C45978 is an unconjugated mouse monoclonal antibody to human CD18 (ITGB2). Validated for Flow, Func, IP and WB.
- Application
- FC, Func, IHC, IP, WB
- Reactivity
- Hu
- Nonreactive Species
- Pig
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD18 antigen | CD18 | Integrin beta chain, beta 2 | ITGB2 | LCAMB | MAC-1 | MFI7 | MF17 | Integrin beta-2 | LAD | LFA-1
- UniProt Number
- P05107
- NCBI GenBank
- NM_000211 | NP_000202.3
- SwissProt
- P05107
Target
- Target
- Human ITGB2 / CD18
- Antigen Species
- Human
- Epitope
- The antibody MEM-148 recognizes an epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18. CD18 (integrin beta2 subunit; beta2 integrin) is a 90-95 kDa type I transmembrane protein expressed on all leukocytes.
- Gene Name
- ITGB2
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- MEM-148
- Isotype
- IgG1
Immunogen
- Immunogen
- Peripheral blood mononuclear cells
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 15 mM Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C. Do not freeze.
- Recommended Storage Buffer
- PBS