LSBio
ITGB2 / CD18 Antibody (Activation Epitope, clone MEM-148)

ITGB2 / CD18 Antibody (Activation Epitope, clone MEM-148)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Flow Cytometry, Immunohistochemistry (general), Immunoprecipitation, Western Blot
Reactivity:Human
Format:Liquid
See all Human ITGB2 / CD18 antibodies →
$392.00each
Catalog Number: LS-C44249-0.2

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Overview

Description
CD18 antibody LS-C44249 is an unconjugated mouse monoclonal antibody to human CD18 (ITGB2) (Activation Epitope). Validated for Flow, IP and WB.
Application
FC, IHC, IP, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD18 antigen | CD18 | Integrin beta chain, beta 2 | ITGB2 | LCAMB | MAC-1 | MFI7 | MF17 | Integrin beta-2 | LAD | LFA-1
UniProt Number
P05107
SwissProt
P05107

Target

Target
Human ITGB2 / CD18
Antigen Species
Human
Epitope
Recognizes an epitope on the human CD18 molecule that is hidden in the CD11/CD18 heterodimer on resting cells. Clone MEM-148 binds very weakly to resting peripheral blood leukocytes and strongly to all leukocytes upon cellular activation. The epitope recognized by MEM-148 is also exposed during dissociation of the CD11/CD18 by low pH.
Gene Name
ITGB2

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
MEM-148
Isotype
IgG1

Immunogen

Immunogen
Peripheral blood mononuclear cells. (ACTIVATION EPITOPE).
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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