LSBio
IHC-plus™ HTT / Huntingtin Antibody (aa2703-2911)

Anti-HTT / Huntingtin antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ HTT / Huntingtin Antibody (aa2703-2911)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:Human, Rabbit
Format:Liquid
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$495.00each
Catalog Number: LS-B6236-50

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Overview

Description
Huntingtin antibody LS-B6236 is an unconjugated mouse monoclonal antibody to Huntingtin (HTT) (aa2703-2911) from human. It is reactive with human and rabbit. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Application
IHC, IHC-F, IHC-P, IP, WB
Reactivity
Hu, Rb
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Huntingtin | Huntington disease protein | IT15 | HD | HTT | HD protein
Recommended Dilution: IHC-P
10 µg/ml
UniProt Number
P42858
SwissProt
P42858

Target

Target
HTT / Huntingtin
Antigen Species
Human
Specificity
Reacts with an epitope corresponding to the human HDC region (2703-2911 amino acids) of the huntingtin protein. Detects a 350kD band on Western Blots but also detects smaller degradation products of Huntingtin. Recognizes both denatured and native Huntingtin in human brain. The combined use of this antibody, LS-C24585 and LS-demonstrates that huntingtin is enriched in neuronal cells in the brain. Species cross-reactivity: rabbit and mouse.
Epitope
Reacts with an epitope corresponding to the human HDC region (2703-2911 amino acids) of the huntingtin protein. Detects a 350kD band on Western Blots but also detects smaller degradation products of Huntingtin. Recognizes both denatured and native Huntingtin in human brain. The combined use of this antibody, LS-C24585 and LS-demonstrates that huntingtin is enriched in neuronal cells in the brain.
Gene Name
HTT

Antibody

Host Species
Mouse
Clonality
Monoclonal
Origin Species
Human

Immunogen

Immunogen
Recombinant protein corresponding to aa 2703-2911 of huntingtin.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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