LSBio
IHC-plus™ GPX4 / MCSP Antibody (aa81-93)

Anti-GPX4 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ GPX4 / MCSP Antibody (aa81-93)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Bovine, Dog, Chicken, Guinea Pig, Goat, Human, Mouse, Non-Human Primate, Pig, Rat
Format:Liquid
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$383.00each
Catalog Number: LS-B1596-1

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Overview

Description
MCSP antibody LS-B1596 is an unconjugated rabbit polyclonal antibody to MCSP (GPX4) (aa81-93) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Application
IHC, IHC-P, WB
Reactivity
Bov, Can, Ck, GP, Gt, Hu, Ms, NHP, Por, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
GPX4 | GPx-4 | MCSP | SnPHGPx | Phospholipid hydroperoxidase | SnGPx | Glutathione peroxidase 4 | GSHPx-4 | PHGPx
Recommended Dilution: IHC-P
10 µg/ml
UniProt Number
P36969
NCBI GenBank
NM_002085 | NP_002076.2
SwissProt
P36969

Target

Target
GPX4 / MCSP
Antigen Species
Human
Specificity
aa81-93 (TQLVDLHARYAEC) of GPX4 / MCSP from human, mouse, rat and other mammals
Epitope
human GPx4 amino acids 81-93 (TQLVDLHARYAEC)
Gene Name
GPX4

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Human GPx4 amino acids 81-93 (TQLVDLHARYAEC). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Goat, Pig, Guinea pig, Turkey, Chicken (100%).

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.2, 0.02% Sodium Azide, 50% Glycerol, 0.1% BSA
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle. Torkamani N, Rufaut NW, Jones L, Sinclair R. Stem cells international. 2016;2016:1286315.

PubMed: 27375744 · PMC: PMC4916308

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke. Ishraq Alim, Joseph T Caulfield, Yingxin Chen, Vivek Swarup, Daniel H Geschwind, Elena Ivanova, Javier Seravalli, Youxi Ai, Lauren H Sansing, Emma J Ste Marie, Robert J Hondal, Sushmita Mukherjee, John W Cave, Botir T Sagdullaev, Saravanan S Karuppagounder, Rajiv R Ratan. Cell. 2019 May;177:1262-1279e25.

PubMed: 31056284

HIF1a stabilization in hypoxia is not oxidant-initiated. Amit Kumar, Manisha Vaish, Saravanan S Karuppagounder, Irina Gazaryan, John W Cave, Anatoly A Starkov, Elizabeth T Anderson, Sheng Zhang, John T Pinto, Austin M Rountree, Wang Wang, Ian R Sweet, Rajiv R Ratan. eLife. 2021 October;10:e72873.

PubMed: 34596045 · PMC: PMC8530508

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