Positive WB detected in:A549 whole cell lysate,MCF-7 whole cell lysate,Mouse kidney tissue,Rat heart tissue;All lanes:GPX4 antibody at 3.5?g/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 23,20 KDa;Observed band size: 23 KDa;
GPX4 / MCSP Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C500054-50
Catalog Number: LS-C500054
For bulk orders or custom formulations:
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- Description
- MCSP antibody LS-C500054 is an unconjugated rabbit polyclonal antibody to MCSP (GPX4) from human. It is reactive with human, mouse and rat. Validated for ELISA, IF, IHC and WB.
- Application
- ELISA, IF, IHC, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- GPX4 | GPx-4 | MCSP | SnPHGPx | Phospholipid hydroperoxidase | SnGPx | Glutathione peroxidase 4 | GSHPx-4 | PHGPx
- UniProt Number
- P36969
- NCBI GenBank
- NM_002085 | NP_002076.2
- SwissProt
- P36969
Target
- Target
- Human GPX4 / MCSP
- Antigen Species
- Human
- Epitope
- Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage. Essential for maturation and survival of photoreceptor cells. Plays a role in a primary T cell response to viral and parasitic infection by protecting T cells from ferroptosis, a cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species, and by supporting T cell expansion.
- Gene Name
- GPX4
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Phospholipid hydroperoxide glutathione peroxidase, mitochondrial protein (74-197AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Concentration
- 7 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS