GZMB / Granzyme B Antibody (clone GB11)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunoprecipitation |
| Reactivity: | Human |
| Format: | Liquid |
$286.00each
Catalog Number: LS-C44295-0.1
Catalog Number: LS-C44295
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- Description
- Granzyme B antibody LS-C44295 is an unconjugated mouse monoclonal antibody to human Granzyme B (GZMB). Validated for ELISA, Flow, IF, IHC and IP.
- Application
- ELISA, FC, IF, IHC, IHC-F, IP
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CCPI | CGL-1 | Cathepsin G-like 1 | CSP-B | CTLA-1 | CTLA1 | CGL1 | CSPB | Fragmentin 2 | GRB | HLP | Human lymphocyte protein | Fragmentin-2 | GZMB | SECT | Lymphocyte protease | T-cell serine protease 1-3E | C11 | CTSGL1 | Cytotoxic serine protease B | Granzyme B | Granzyme-2
- Recommended Dilution: ELISA
- 2 - 5 ug/ml
- Recommended Dilution: FC
- 1:10 - 1:100
- UniProt Number
- P10144
- NCBI GenBank
- NM_004131 | NP_004122.2
- SwissProt
- P10144
Target
- Target
- Human GZMB / Granzyme B
- Antigen Species
- Human
- Epitope
- Recognizes the serine protease Granzyme B, which is important in the induction of apoptosis in target cells by cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell, Granzyme B activates the cascade of caspases that finally results in cell death. Has been reported to function as a capture reagent in ELISA assays for soluble Granzyme B in conjunction with biotin conjugated clone GB10 (MCA2119B) as detection reagent.
- Gene Name
- GZMB
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- GB11
- Isotype
- IgG1
Immunogen
- Immunogen
- Purified human Granzyme B.
- Immunogen Type
- Native Protein (Purified from Natural Source)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- TBS, 0.09% Sodium Azide
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- TBS