GZMB / Granzyme B Antibody
Catalog Number: LS-C662628-100
100 µg / $480.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity: Mouse
Format: Lyophilized
Anti-GZMB / Granzyme B antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
IHC-plus™ GZMB / Granzyme B Antibody (aa10-59)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$383.00each
Catalog Number: LS-B7602-50
Catalog Number: LS-B7602
For bulk orders or custom formulations:
Request a QuoteOverview
- Description
- Granzyme B antibody LS-B7602 is an unconjugated rabbit polyclonal antibody to Granzyme B (GZMB) (aa10-59) from human. It is reactive with human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
- Application
- ELISA, IHC, IHC-P, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- CCPI | CGL-1 | Cathepsin G-like 1 | CSP-B | CTLA-1 | CTLA1 | CGL1 | CSPB | Fragmentin 2 | GRB | HLP | Human lymphocyte protein | Fragmentin-2 | GZMB | SECT | Lymphocyte protease | T-cell serine protease 1-3E | C11 | CTSGL1 | Cytotoxic serine protease B | Granzyme B | Granzyme-2
- Recommended Dilution: IHC-P
- 1:200
- Recommended Dilution: WB
- 1:500 - 1:1000
- UniProt Number
- P10144
- NCBI GenBank
- NM_004131 | NP_004122.2
- SwissProt
- P10144
Target
- Target
- GZMB / Granzyme B
- Antigen Species
- Human
- Specificity
- Granzyme B Antibody detects endogenous levels of total Granzyme B protein.
- Epitope
- Granzyme B Antibody detects endogenous levels of total Granzyme B protein.
- Gene Name
- GZMB
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide from human Granzyme B. (AA Range: 8-59)
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
- Concentration
- 1 mg/mL
- Volume
- 50 Microliter
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C for up to 1 year.
- Recommended Storage Buffer
- PBS, 150 mM NaCl
Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability. Nalle SC, Zuo L, Ong MLDM, Singh G, Worthylake AM, Choi W, Manresa MC, Southworth AP, Edelblum KL, Baker GJ, Joseph NE, Savage PA, Turner JR. The Journal of clinical investigation. 2019 February;129:902-914.
PubMed: 30667372 · PMC: PMC6355225
Single-cell analysis shows that adipose tissue of persons with both HIV and diabetes is enriched for clonal, cytotoxic, and CMV-specific CD4+ T cells. Celestine N Wanjalla, Wyatt J McDonnell, Ramesh Ram, Abha Chopra, Rama Gangula, Shay Leary, Mona Mashayekhi, Joshua D Simmons, Christian M Warren, Samuel Bailin, Curtis L Gabriel, Liang Guo, Briana D Furch, Morgan C Lima, Beverly O Woodward, LaToya Hannah, Mark A Pilkinton, Daniela T Fuller, Kenji Kawai, Renu Virmani, Aloke V Finn, Alyssa H Hasty, Simon A Mallal, Spyros A Kalams, John R Koethe. Cell reports. Medicine. 2021 February;2:100205.
PubMed: 33665640 · PMC: PMC7897802
