GZMB / Granzyme B Antibody (clone GB7)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$286.00each
Catalog Number: LS-C11635-0.1
Catalog Number: LS-C11635
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- Description
- Granzyme B antibody LS-C11635 is an unconjugated mouse monoclonal antibody to human Granzyme B (GZMB). Validated for IHC.
- Application
- IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CCPI | CGL-1 | Cathepsin G-like 1 | CSP-B | CTLA-1 | CTLA1 | CGL1 | CSPB | Fragmentin 2 | GRB | HLP | Human lymphocyte protein | Fragmentin-2 | GZMB | SECT | Lymphocyte protease | T-cell serine protease 1-3E | C11 | CTSGL1 | Cytotoxic serine protease B | Granzyme B | Granzyme-2
- Recommended Dilution: IHC-P
- 1:50 - 1:200
- UniProt Number
- P10144
- NCBI GenBank
- NM_004131 | NP_004122.2
- SwissProt
- P10144
Target
- Target
- Human GZMB / Granzyme B
- Antigen Species
- Human
- Epitope
- Recognizes the serine protease Granzyme B, which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death.
- Gene Name
- GZMB
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- GB7
- Isotype
- IgG2a
Immunogen
- Immunogen
- Recombinant Granzyme B.
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- TBS, 0.01% Thimerosal
- Preservative
- Yes
- Purification Method
- Unpurified (Serum / Ascites / Supernatant)
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- TBS