Positive WB detected in:Mouse lung tissue,Mouse kidney tissue;All lanes:CDH5 antibody at 3ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 88,75 kDa;Observed band size: 88 kDa;
CD144 / CDH5 / VE Cadherin Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$300.00each
Catalog Number: LS-C500157-50
Catalog Number: LS-C500157
For bulk orders or custom formulations:
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- Description
- VE Cadherin antibody LS-C500157 is an unconjugated rabbit polyclonal antibody to VE Cadherin (CD144 / CDH5) from human. It is reactive with human and mouse. Validated for ELISA, IF and WB.
- Application
- ELISA, IF, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- 7B4 | 7B4 antigen | CD144 | CDH5 | Cadherin-5 | Endothelial-specific cadherin | Vascular endothelial cadherin | VE-cadherin | VEC | CD144 antigen | VE Cadherin
- UniProt Number
- P33151
- NCBI GenBank
- NM_001795 | NP_001786.2
- SwissProt
- P33151
Target
- Target
- Human CD144 / CDH5 / VE Cadherin
- Antigen Species
- Human
- Epitope
- Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
- Gene Name
- CDH5
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant Human Cadherin-5 protein (349-569AA)
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS