LSBio
Mouse EPCAM Protein (Recombinant Fc, C-terminus)

Mouse EPCAM Protein (Recombinant Fc, C-terminus)

ProteinLSBio Guarantee
Expression SystemOther
Format:Lyophilized
See all EPCAM antibodies →
$253.00each
Catalog Number: LS-G137857-10

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Overview

Description
Epithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its' monomer subunit structure interacts with phosphorylated CLDN7. Ep-CAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cells proliferation and differentiation. It also up-regulates the expression of FABP5, MYC and cyclins A and E. The post-translational modification glycosylation at Asn-198 is crucial for protein stability.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
323/A3 | ACSTD1 | 17-1A | CD326 | EGP | EGP34 | Epithelial glycoprotein | GA733-2 | HNPCC8 | Ep-CAM | ESA | HEGP314 | KS 1/4 antigen | KS1/4 | KSA | M1S2 | MIC18 | MK-1 | MH99 | TROP1 | TACST-1 | TACSTD1 | CD326 antigen | CO-17A | DIAR5 | EGP-2 | EGP314 | EGP40 | EPCAM | Epithelial glycoprotein 314 | HEA125 | Ly74 | M4S1
Origin Species
Ms
NCBI GenBank
NM_002354
SwissProt
P16422

Protein

Expression System
Other
Fusion Tag
hFc
Protein Type
Recombinant
Amino Acid Sequence
1QRDCVCDNYK LATSCSLNEY GECQCTSYGT QNTVICSKLA SKCLAMKAEM THSKSGRRIK
61PEGAIQNNDG LYDPDCDEQG LFKAKQCNGT ATCWCVNTAG VRRTDKDTEI TCSERVRTYW
121IIIELKHKER ESPYDHQSLQ TALQEAFTSR YKLNQKFIKN IMYENNVITI DLMQNSSQKT
181QDDVDIADVA YYFEKDVKGE SLFHSSKSMD LRVNGEPLDL DPGQTLIYYV DEKAPEFSMQ
241GLTVDDIEGR MDEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV
301VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV
361SNKALPAPIE KTISKAKGQP REPQVYTLPP SREEMTKNQV SLTCLVKGFY PSDIAVEWES
421NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL
481SPGK

484 aa

Format

Purity
>95%
Conjugate/Label
Unconj
Endotoxin Level
< 1 EU/µg
Format
Lyophilized
Formulation
Lyophilized from a sterile solution in PBS, pH 7.4.
Purity Measurement Method
SDS-PAGE

Storage & Handling

Storage Conditions
Before reconstitution: short term; store at room temperature for up to 3 weeks, long term; store at -20°C. After Reconstitution: short term; store at 4°C to 7°C for up to 7 days, long term; Aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.

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