LSBio
Human SERPINE1 / PAI-1 Protein (Recombinant His)

Human SERPINE1 / PAI-1 Protein (Recombinant His)

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Expression SystemEscherichia coli (Prokaryotic)
Format:Liquid
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$267.00each
Catalog Number: LS-G3515-20

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Overview

Description
Plasminogen activator inhibitor-1(PAI-1), a member of the serine protease inhibitor(serpin) super family. PAI-1 is the principal inhibitor of tissue plasminogen activator and urokinase, the activators of plasminogen and hence fibrinolysis. PAI-1 is mainly produced by the endothelium but is also secreted by other tissue types, such as adipose tissue. Recombinant human PAI-1, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Category
Proteins & Peptides > Proteins > Recombinant Proteins
Alternative Names
PAI1 | PLANH1 | SERPINE1 | PAI-1 | Serpin E1
Origin Species
Human
NCBI GenBank
NM_000602|NP_000593.1
SwissProt
P05121

Protein

Expression System
Escherichia coli (Prokaryotic)
Fusion Tag
Hexahistidine Tag
Protein Type
Recombinant
Amino Acid Sequence
124-402aa|M GSSHHHHHHS SGLVPRGSHM VHHPPSYVAH LASDFGVRVF QQVAQASKDR
61NVVFSPYGVA SVLAMLQLTT GGETQQQIQA AMGFKIDDKG MAPALRHLYK ELMGPWNKDE
121ISTTDAIFVQ RDLKLVQGFM PHFFRLFRST VKQVDFSEVE RARFIINDWV KTHTKGMISN
181LLGKGAVDQL TRLVLVNALY FNGQWKTPFP DSSTHRRLFH KSDGSTVSVP MMAQTNKFNY
241TEFTTPDGHY YDILELPYHG DTLSMFIAAP YEKEVPLSAL TNILSAQLIS HWKGNMTRLP
301RLLVLPKFSL ETEVDLRKPL ENLGMTDMFR QFQADFTSLS DQEPLHVAQA LQKVKIEVNE
361SGTVASSSTA VIVSARMAPE EIIMDRPFLF VVRHNPTGTV LFMGQVMEP

409 aa

Format

Purity
>95%
Conjugate/Label
Unconjugated
Endotoxin Level
Not Tested
Format
Liquid
Formulation
50mM NaAc (pH 5.5) containing 10% glycerol, 0.1M NaCl.
Purity Measurement Method
SDS-PAGE (Coomassie Stain)

Storage & Handling

Storage Conditions
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.

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