Formalin-fixed, paraffin-embedded human Pancreas stained with Spectrin alpha 1 Rabbit Recombinant Monoclonal Antibody (SPTA1/2939R).
SPTA1 / Alpha Spectrin Antibody (aa356-475, clone SPTA1/2939R)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$379.00each
Catalog Number: LS-C751375-20
Catalog Number: LS-C751375
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- Description
- Alpha Spectrin antibody LS-C751375 is an unconjugated rabbit recombinant monoclonal antibody to human Alpha Spectrin (SPTA1) (aa356-475). Validated for ELISA, IHC and WB.
- Application
- ELISA, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- EL2 | Erythroid alpha-spectrin | HS3 | Alpha-I spectrin | SPTA1 | HPP | SPH3 | SPTA
- Recommended Dilution: ELISA
- 2 - 4 ug/ml
- Recommended Dilution: IHC-P
- 1 - 2 µg/ml
- Recommended Dilution: WB
- 1 - 2 µg/ml
- UniProt Number
- P02549
- NCBI GenBank
- NM_003126 | NP_003117.2
- SwissProt
- P02549
Target
- Target
- Human SPTA1 / Alpha Spectrin
- Antigen Species
- Human
- Epitope
- Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous alpha and beta chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin alpha I and spectrin beta I are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrin beta II (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.
- Gene Name
- SPTA1
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- SPTA1/2939R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant fragment of human SPTA (around aa356-475). Antigen Molecular Weight: 240 kDa
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 µg/mL
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS