LSBio
Recombinant Monoclonal Mouse anti-Human SPTA1 / Alpha Spectrin Antibody (clone rSPTA1/1833, aa356-475, IHC, WB)

Formalin-fixed, paraffin-embedded Human Placenta stained with Spectrin alpha 1 Mouse Recombinant Monoclonal Antibody (rSPTA1/1833).

Recombinant Monoclonal Mouse anti-Human SPTA1 / Alpha Spectrin Antibody (clone rSPTA1/1833, aa356-475, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Recombinant Monoclonal
Applications:Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
See all Human SPTA1 / Alpha Spectrin antibodies →
$379.00each
Catalog Number: LS-C751373-20

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Overview

Description
Alpha Spectrin antibody LS-C751373 is an unconjugated mouse recombinant monoclonal antibody to human Alpha Spectrin (SPTA1) (aa356-475). Validated for IHC and WB.
Application
IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
EL2 | Erythroid alpha-spectrin | HS3 | Alpha-I spectrin | SPTA1 | HPP | SPH3 | SPTA
Recommended Dilution: IHC-P
1 - 2 µg/ml
Recommended Dilution: WB
1 - 2 µg/ml
UniProt Number
P02549
SwissProt
P02549

Target

Target
Human SPTA1 / Alpha Spectrin
Antigen Species
Human
Epitope
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous alpha and beta chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin alpha I and spectrin beta I are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrin beta II (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.
Gene Name
SPTA1

Antibody

Host Species
Mouse
Clonality
Recombinant Monoclonal
Clone
rSPTA1/1833
Isotype
IgG1
Origin Species
Human

Immunogen

Immunogen
Recombinant fragment of human SPTA (around aa356-475). Antigen Molecular Weight: 240 kDa
Immunogen Type
Recombinant Protein Fragment

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Preservative
Yes
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.