SIGLEC1 / CD169 / Sialoadhesin Antibody (clone ED3)

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Antibody:	Mouse Monoclonal
Applications:	Flow Cytometry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunoprecipitation
Reactivity:	Rat
Format:	Liquid

$296.00each

Catalog Number: LS-C45080-0.1

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Description: Sialoadhesin antibody LS-C45080 is an unconjugated mouse monoclonal antibody to rat Sialoadhesin (SIGLEC1 / CD169). Validated for Flow, IF, IHC and IP.
Application: FC, IF, IHC, IHC-F, IP
Reactivity: Rt
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: CD169 | CD169 antigen | SIGLEC-1 | SIGLEC1 | Sialoadhesin | SN | DJ1009E24.1
Recommended Dilution: FC: 1:500
Recommended Dilution: IHC-F: 1:250
UniProt Number: Q9BZZ2
NCBI GenBank: NM_023068 | NP_075556.1
SwissProt: Q9BZZ2

Target: Rat SIGLEC1 / CD169 / Sialoadhesin
Antigen Species: Rat
Epitope: Recognizes the rat CD169 cell surface antigen, a 185kD molecule expressed by macrophages, predominately confined to lymphoid organs only. Monocytes and granulocytes are negative. No other cell types are positive. The most conspicuous property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly. Furthermore, macrophages in (auto-immune) diseased tissues express the ED3 antigen. In healthy tissue no expression occurs. CD169 is a receptor for glycoconjugates containing sialic acid.
Gene Name: SIGLEC1

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS

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