LSBio
Polyclonal Rabbit anti-Human AGO2 / EIF2C2 Antibody (WB)

The Slicer Antibody is used in Western blot to detect Slicer in MDA-MB-435 cell lysate.

Polyclonal Rabbit anti-Human AGO2 / EIF2C2 Antibody (WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
See all Human AGO2 / EIF2C2 antibodies →
$402.00each
Catalog Number: LS-C413766-0.1

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Overview

Description
EIF2C2 antibody LS-C413766 is an unconjugated rabbit polyclonal antibody to EIF2C2 (AGO2) from human. It is reactive with human, mouse and rat. Validated for ELISA and WB.
Application
ELISA, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
AGO2 | Argonaute2 | Argonaute 2 | EIF-2C 2 | EIF2C2 | EIF2C 2 | HAgo2 | PPD | Protein slicer | Q10 | PAZ Piwi domain protein | Protein argonaute-2
Recommended Dilution: ELISA
1:500 - 1:1000
Recommended Dilution: WB
1:100 - 1:500

Target

Target
Human AGO2 / EIF2C2
Antigen Species
Human
Epitope
Eukaryotic translation initiation factor 2C 2, also known as Slicer protein or Argonaute-2, provides endonuclease activity to RNA-induced silencing complexes (RISC). Slicer cleaves siRNA/mRNA heteroduplexes bound to RISC. Slicer is essential for embryonic development and RNA-mediated gene silencing (RNAi). Slicer is localised in processing bodies (P bodies) that contain decapping enzymes, a 5'-to-3' exoribonuclease, LSm proteins, and RNAi machinery components.

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
KLH-conjugated synthetic peptide from the N-Terminus of human Slicer.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.09% Sodium Azide
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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