LSBio
PathPlus™ Polyclonal Rabbit anti-Human PDCD4 Antibody (IHC, WB)

Anti-PDCD4 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

PathPlus™ Polyclonal Rabbit anti-Human PDCD4 Antibody (IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
See all PDCD4 antibodies →
$383.00each
Catalog Number: LS-B1388-50

For bulk orders or custom formulations:

Request a Quote

Overview

Description
PDCD4 antibody LS-B1388 is an unconjugated rabbit polyclonal antibody to PDCD4 from human. It is reactive with human, mouse and rat. Validated for ELISA, IHC and WB. Cited in 3 publications.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
H731 | Nuclear antigen H731-like | Nuclear antigen H731 | PDCD4 | Protein 197/15a
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
0.5 - 1 µg/ml
UniProt Number
Q53EL6
SwissProt
Q53EL6

Target

Target
PDCD4
Antigen Species
Human
Gene Name
PDCD4

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
A 19 amino acid synthetic peptide near the C-Terminus of human PDCD4. The immunogen is located within the last 50 amino acids of PDCD4.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS containing 0.02% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS

Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer. Alder H, Taccioli C, Chen H, Jiang Y, Smalley KJ, Fadda P, Ozer HG, Huebner K, Farber JL, Croce CM, Fong LY. Carcinogenesis. 2012 Sep;33:1736-44.

PubMed: 22689922 · PMC: PMC3514898


MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency. Fong LY, Taccioli C, Jing R, Smalley KJ, Alder H, Jiang Y, Fadda P, Farber JL, Croce CM. Oncotarget. 2016;7:10723-38.

PubMed: 26918602 · PMC: PMC4905434


Zinc treatment reverses and anti-Zn-regulated miRs suppress esophageal carcinomas in vivo. Louise Y Fong, Kay Huebner, Ruiyan Jing, Karl J Smalley, Christopher R Brydges, Oliver Fiehn, John L Farber, Carlo M Croce. Proceedings of the National Academy of Sciences of the United States of America. 2023 May;120:e2220334120.

PubMed: 37155893 · PMC: PMC10193985

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.