NALP3 / NLRP3 Antibody
Catalog Number: LS-C499430
2 sizes / from $300.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general)
Reactivity: Human
Format: Liquid
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
PathPlus™ NALP3 / NLRP3 Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$556.00each
Catalog Number: LS-B4321-0.05
Catalog Number: LS-B4321
For bulk orders or custom formulations:
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- Description
- NLRP3 antibody LS-B4321 is an unconjugated rabbit polyclonal antibody to NLRP3 (NALP3) from human. It is reactive with human and mouse. Validated for ELISA, ICC, IF, IHC and WB. Cited in 7 publications.
- Application
- ELISA, ICC, IF, IHC, IHC-P, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- AGTAVPRL | AII | C1orf7 | Caterpiller protein 1.1 | Cryopyrin | FCAS | FCU | NLRP3 | PYPAF1 | NALP3 | CIAS1 | CLR1.1 | MWS
- Recommended Dilution: IF/ICC
- 2 µg/ml; 20 µg/ml
- Recommended Dilution: IHC-P
- 2.5 - 5 µg/ml
- Recommended Dilution: WB
- 1 µg/ml
- UniProt Number
- Q96P20
- NCBI GenBank
- NM_004895 | NP_004886.3
- SwissProt
- Q96P20
Target
- Target
- NALP3 / NLRP3
- Antigen Species
- Human
- Gene Name
- NLRP3
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- A 16 AA synthetic peptide near the N-Terminus of human NALP3. The immunogen is located within aa 120-170 of NALP3.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS containing 0.02% Sodium Azide
- Concentration
- 1 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
- Recommended Storage Buffer
- PBS
Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS. Walsh JG, Reinke SN, Mamik MK, McKenzie BA, Maingat F, Branton WG, Broadhurst DI, Power C. Retrovirology. 2014;11:35.
PubMed: 24886384 · PMC: PMC4038111
High fat diet dysregulates microRNA-17-5p and triggers retinal inflammation: Role of endoplasmic-reticulum-stress. Coucha M, Mohamed IN, Elshaer SL, Mbata O, Bartasis ML, El-Remessy AB. World journal of diabetes. 2017;8:56-65.
PubMed: 28265343 · PMC: PMC5320749
Deletion of Thioredoxin-Interacting Protein (TXNIP) Abrogates High Fat Diet-induced Retinal Leukostasis, Barrier Dysfunction and Microvascular Degeneration in a Mouse Obesity Model. Islam N Mohamed, Nader Sheibani, Azza B El-Remessy. International journal of molecular sciences. 2020 June;21.
PubMed: 32492941 · PMC: PMC7312035
Embryonic stem cell-derived exosomes inhibit doxorubicin-induced TLR4-NLRP3-mediated cell death-pyroptosis. Zahra Tavakoli Dargani, Dinender K Singla. American journal of physiology. Endocrinology and metabolism. 2019 August;317:H460-H471.
PubMed: 31172809 · PMC: PMC6732475
Deletion of TXNIP Mitigates High-Fat Diet-Impaired Angiogenesis and Prevents Inflammation in a Mouse Model of Critical Limb Ischemia. Sally L Elshaer, Islam N Mohamed, Maha Coucha, Sara Altantawi, Wael Eldahshan, Megan L Bartasi, Ahmed Y Shanab, Renee Lorys, Azza B El-Remessy. Antioxidants (Basel, Switzerland). 2017 Jun;6:47.
PubMed: 28661427 · PMC: PMC5618075
Modulating Expression of Thioredoxin Interacting Protein (TXNIP) Prevents Secondary Damage and Preserves Visual Function in a Mouse Model of Ischemia/Reperfusion. Maha Coucha, Ahmed Y Shanab, Mohamed Sayed, Almira Vazdarjanova, Azza B El-Remessy. International journal of molecular sciences. 2019 Aug;20:3969.
PubMed: 31443163 · PMC: PMC6721134
Modulating Expression of Thioredoxin Interacting Protein (TXNIP) Prevents Secondary Damage and Preserves Visual Function in a Mouse Model of Ischemia/Reperfusion. Ibolya E András, Marta Garcia-Contreras, Christopher Yanick, Paola Perez, Brice Sewell, Leonardo Durand, Michal Toborek. Molecular brain. 2019 Feb;13:21.
PubMed: 32066471 · PMC: PMC7027073
