Western blot analysis of extracts of K-562 cell line, using NLRP3 antibody.
NALP3 / NLRP3 Antibody
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
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- Description
- NLRP3 antibody LS-C334192 is an unconjugated rabbit polyclonal antibody to NLRP3 (NALP3) from human. It is reactive with human, mouse and rat. Validated for WB. Cited in 3 publications.
- Application
- IHC, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- AGTAVPRL | AII | C1orf7 | Caterpiller protein 1.1 | Cryopyrin | FCAS | FCU | NLRP3 | PYPAF1 | NALP3 | CIAS1 | CLR1.1 | MWS
- Recommended Dilution: WB
- 1:500 - 1:2000
- UniProt Number
- Q96P20
- NCBI GenBank
- NM_004895 | NP_004886.3
- SwissProt
- Q96P20
Target
- Target
- Human NALP3 / NLRP3
- Antigen Species
- Human
- Epitope
- Human NALP3 / NLRP3
- Gene Name
- NLRP3
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant protein of human NLRP3
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol
- Volume
- 20 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Fructose stimulated de novo lipogenesis is promoted by inflammation. Jelena Todoric, Giuseppe Di Caro, Saskia Reibe, Darren C Henstridge, Courtney R Green, Alison Vrbanac, Fatih Ceteci, Claire Conche, Reginald McNulty, Shabnam Shalapour, Koji Taniguchi, Peter J Meikle, Jeramie D Watrous, Rafael Moranchel, Mahan Najhawan, Mohit Jain, Xiao Liu, Tatiana Kisseleva, Maria T Diaz-Meco, Jorge Moscat, Rob Knight, Florian R Greten, Lester F Lau, Christian M Metallo, Mark A Febbraio, Michael Karin. Nature metabolism. 2020 October;2:1034-1045.
PubMed: 32839596 · PMC: PMC8018782
Blockade of ß-adrenergic signaling suppresses inflammasome and alleviates cardiac fibrosis. Shipeng Dang, Zhen-Ye Zhang, Ku-Lin Li, Jie Zheng, Ling-Ling Qian, Xiao-Yu Liu, Ying Wu, Chang-Ying Zhang, Xiao-Xi Zhao, Zhi-Ming Yu, Ru-Xing Wang, Tingbo Jiang. Annals of translational medicine. 2020 February;8:127.
PubMed: 32175420 · PMC: PMC7048978
NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation. Francis M Hughes Jr, Nathan A Hirshman, Brian M Inouye, Huixia Jin, Eloise W Stanton, Chloe E Yun, Leah G Davis, Jonathan C Routh, J Todd Purves. Diabetes. 2019 Feb;68:430-440.
PubMed: 30425063 · PMC: PMC6341307