NALP3 / NLRP3 Antibody
Catalog Number: LS-C499430
2 sizes / from $300.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general)
Reactivity: Human
Format: Liquid
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
PathPlus™ NALP3 / NLRP3 Antibody (aa158-207)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$383.00each
Catalog Number: LS-B8262-100
Catalog Number: LS-B8262
For bulk orders or custom formulations:
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- Description
- NLRP3 antibody LS-B8262 is an unconjugated rabbit polyclonal antibody to human NLRP3 (NALP3) (aa158-207). Validated for IHC and WB. Cited in 2 publications.
- Application
- IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- AGTAVPRL | AII | C1orf7 | Caterpiller protein 1.1 | Cryopyrin | FCAS | FCU | NLRP3 | PYPAF1 | NALP3 | CIAS1 | CLR1.1 | MWS
- Recommended Dilution: IHC-P
- 5 µg/ml
- UniProt Number
- Q96P20
- NCBI GenBank
- NM_004895 | NP_004886.3
- SwissProt
- Q96P20
Target
- Target
- NALP3 / NLRP3
- Antigen Species
- Human
- Specificity
- Human NLRP3. Immunogenic peptide shares 75% homology with the mouse sequence. The antibody has not been specifically tested with mouse samples at this time. Cross-reactivity or lack thereof therefore cannot be guaranteed.
- Epitope
- Human NLRP3. Immunogenic peptide shares 75% homology with the mouse sequence. The antibody has not been specifically tested with mouse samples at this time. Cross-reactivity or lack thereof therefore cannot be guaranteed.
- Gene Name
- NLRP3
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide located between aa158-207 of human NLRP3 (Q96P20, NP_004886). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Galago, Bovine, Rabbit, Horse, Pig (92%); Bat (85%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% sodium azide, 2% sucrose
- Concentration
- 0.5 mg/mL
- Volume
- 100 Microliter
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
- Recommended Storage Buffer
- PBS
Implication of the NLRP3 Inflammasome in Bovine Age-Related Sarcopenia. Davide De Biase, Giuseppe Piegari, Francesco Prisco, Ilaria Cimmino, Ilaria d'Aquino, Valeria Baldassarre, Francesco Oriente, Serenella Papparella, Orlando Paciello. International journal of molecular sciences. 2021 Mar;22:3609.
PubMed: 33808510 · PMC: PMC8036417
Autophagy and NLRP3 inflammasome crosstalk in neuroinflammation in aged bovine brains. Davide De Biase, Giuseppe Piegari, Francesco Prisco, Ilaria Cimmino, Claudio Pirozzi, Giuseppina Mattace Raso, Francesco Oriente, Edoardo Grieco, Serenella Papparella, Orlando Paciello. Journal of cellular physiology. 2020 June;235:5394-5403.
PubMed: 31903559
