LSBio
PathPlus™ NALP3 / NLRP3 Antibody (aa158-207)

Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ NALP3 / NLRP3 Antibody (aa158-207)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
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$383.00each
Catalog Number: LS-B8262-100

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Overview

Description
NLRP3 antibody LS-B8262 is an unconjugated rabbit polyclonal antibody to human NLRP3 (NALP3) (aa158-207). Validated for IHC and WB. Cited in 2 publications.
Application
IHC, IHC-P, WB
Reactivity
Hu
Intended Use
RUO
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
AGTAVPRL | AII | C1orf7 | Caterpiller protein 1.1 | Cryopyrin | FCAS | FCU | NLRP3 | PYPAF1 | NALP3 | CIAS1 | CLR1.1 | MWS
Recommended Dilution: IHC-P
5 µg/ml
UniProt Number
Q96P20
NCBI GenBank
NM_004895, NP_004886.3
SwissProt
Q96P20

Target

Target
NALP3 / NLRP3
Antigen Species
Hu
Specificity
Human NLRP3. Immunogenic peptide shares 75% homology with the mouse sequence. The antibody has not been specifically tested with mouse samples at this time. Cross-reactivity or lack thereof therefore cannot be guaranteed.
Epitope
Human NLRP3. Immunogenic peptide shares 75% homology with the mouse sequence. The antibody has not been specifically tested with mouse samples at this time. Cross-reactivity or lack thereof therefore cannot be guaranteed.
Gene Name
NLRP3

Antibody

Host Species
Rb
Clonality
Polyclonal
Origin Species
Hu

Immunogen

Immunogen
Synthetic peptide located between aa158-207 of human NLRP3 (Q96P20, NP_004886). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Galago, Bovine, Rabbit, Horse, Pig (92%); Bat (85%).

Format

Conjugate/Label
Unconj
Format
Liquid
Formulation
PBS, 0.09% sodium azide, 2% sucrose
Concentration
0.5 mg/mL
Volume
100 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
AP

Storage & Handling

Storage Conditions
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS
Implication of the NLRP3 Inflammasome in Bovine Age-Related Sarcopenia. Davide De Biase, Giuseppe Piegari, Francesco Prisco, Ilaria Cimmino, Ilaria d'Aquino, Valeria Baldassarre, Francesco Oriente, Serenella Papparella, Orlando Paciello. International journal of molecular sciences. 2021 Mar;22:3609. PubMed: 33808510 PMC: PMC8036417
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