Immunofluorescence analysis of U2OS cell using NPHP1 antibody. Blue: DAPI for nuclear staining.
NPHP1 / Nephronophthisis Antibody (aa463-732)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunofluorescence, Immunohistochemistry (general), Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$281.00each
Catalog Number: LS-C334864-20
Catalog Number: LS-C334864
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- Description
- Nephronophthisis antibody LS-C334864 is an unconjugated rabbit polyclonal antibody to Nephronophthisis (NPHP1) (aa463-732) from human. It is reactive with human, mouse and rat. Validated for IF, IHC and WB. Cited in 1 publication.
- Application
- IF, IHC, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- JBTS4 | Nephrocystin 1 | Nephronophthisis | SLSN1 | Nephrocystin-1 | Nephronophthisis 1 (juvenile) | NPH1 | NPHP1
- Recommended Dilution: IF/ICC
- 1:50 - 1:100
- Recommended Dilution: IHC
- 1:50 - 1:200
- Recommended Dilution: WB
- 1:500 - 1:2000
- UniProt Number
- O15259
- NCBI GenBank
- NM_000272 | NP_000263.2
- SwissProt
- O15259
Target
- Target
- Human NPHP1 / Nephronophthisis
- Antigen Species
- Human
- Epitope
- Human NPHP1 / Nephronophthisis
- Gene Name
- NPHP1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 345-614 of human NPHP1 (NP_001121651.1). PDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFYRQILGDVLLKDRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETARWKVITDFLKQNQENQGALQALLSPDGVHEPFDLSEQTYDFLGEMRKNAV
- Immunogen Type
- Fusion Protein (e.g., GST, MBP tag)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol
- Volume
- 20 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
An Nphp1 knockout mouse model targeting exon 2-20 demonstrates characteristic phenotypes of human nephronophthisis. Dantong Li, Miaoyue Hu, Huamu Chen, Xiaohong Wu, Xiaoya Wei, Hongrong Lin, Xuefei Gao, Haiyan Wang, Min Li, Albert C M Ong, Zhihui Yue, Liangzhong Sun. Human molecular genetics. 2021 December;31:232-243. PubMed: 34415307